???Meta-analysis??? Clarifies Birth Conditions Associated with Autism ?? Autism Speaks Official Blog

by Kelly Thomas Reardon

Such a ???meta-analysis??? study is a powerful tool in science, as it allows researchers to combine and compare findings from different sources to get a clearer, more reliable picture of the associations between potential risks and conditions such as autism. Importantly, the study confirmed an association between autism and such conditions as abnormal fetal presentation during delivery (for example, breech), fetal respiratory distress (breathing difficulties), birth injury or trauma, low 5-minute APGAR score (a 1-10 score for assessing newborn health after delivery), newborn seizures, low birth weight, multiple births (twins, triplets, etc.), anemia (low blood iron, and being born in the summer.

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One common thread across several of these risk factors is that they result in a lack of adequate blood flow to the brain during the birth process. One hypothesis is that, when combined with a genetic predisposition, oxygen deprivation to the brain worsens abnormal brain development. Studying these and other environmental (versus genetic) risk factors for autism is important to increase our understanding of the biology of ASD and to provide practical guidance for physicians and parents on how to avoid or modify those risk factors that can be changed.

Lots of interesting studies going on lately in regards to environmental factors (as opposed to genetic factors) in regards to Autism Spectrum Disorders (ASD). Quick read and interesting to think about, although obviously not conclusive by any regard.

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